Integrative in silico and in vitro approach for clarifying mode of action to activate estrogen receptor alpha and lipid accumulation by methiocarb

Disruption of estrogen receptor alpha (ERα) by endocrine-active pesticides may contribute to lipid metabolic dysregulation. We aimed to clarify the docking dynamics of methiocarb with ERα and evaluate its potential to induce lipid accumulation through ERα activation using non-animal testing systems....

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Bibliografski detalji

Glavni autori:	Da-Hyun Jeong, Rajesh Kumar Pathak, Eunhee Lee, Jun-Mo Kim, Hee-Seok Lee
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-09-01
Serija:	Ecotoxicology and Environmental Safety
Teme:	Methiocarb Estrogen receptor alpha Binding affinity Agonist Lipid accumulation
Online pristup:	http://www.sciencedirect.com/science/article/pii/S0147651325011443
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