Primary Cells from a <i>CD46</i>-Edited Bovine Heifer Have Reduced BVDV Susceptibility Despite Viral Adaptation to Heparan Sulfate
A precision genome edit in the bovine <i>CD46</i> gene (A<sub>82</sub>LPTFS<sub>87</sub>) dramatically reduced bovine viral diarrhea virus (BVDV) susceptibility in a cloned heifer. However, pathogen evolution threatens the long-term efficacy of such interventions. Here, our aim is two-fold: first, t...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI AG
2025-04-01
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| Colección: | Viruses |
| Materias: | |
| Acceso en línea: | https://www.mdpi.com/1999-4915/17/5/634 |
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