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A CRISPR/Cas9 Generated Bovine CD46-knockout Cell Line—A Tool to Elucidate the Adaptability of Bovine Viral Diarrhea Viruses (BVDV)

Bovine viral diarrhea virus (BVDV) entry into a host cell is mediated by the interaction of the viral glycoprotein E2 with the cellular transmembrane CD46 receptor. In this study, we generated a stable Madin–Darby Bovine Kidney (MDBK) CD46-knockout cell line to study the ability of different <i>pest...

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Autors principals: Kevin P. Szillat, Susanne Koethe, Kerstin Wernike, Dirk Höper, Martin Beer
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-08-01
Col·lecció:Viruses
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Accés en línia:https://www.mdpi.com/1999-4915/12/8/859
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