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Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy

BackgroundThe effectiveness of immunomodulatory therapies in sepsis is often hampered by profound and patient-specific immune heterogeneity. Classical monocytes play a central role in the progression toward sepsis-induced immunoparalysis, with their apoptotic rate serving as a sensitive marker of im...

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Detaylı Bibliyografya
Asıl Yazarlar: Wenjuan Duan, Qi Chen, Wei Li, Haiying Zhou, Xiaorong Deng, Yan Zhang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2025-10-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fphar.2025.1675887/full
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