Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy
BackgroundThe effectiveness of immunomodulatory therapies in sepsis is often hampered by profound and patient-specific immune heterogeneity. Classical monocytes play a central role in the progression toward sepsis-induced immunoparalysis, with their apoptotic rate serving as a sensitive marker of im...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2025-10-01
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| Schriftenreihe: | Frontiers in Pharmacology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1675887/full |
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