PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus

Abstract Background Diabetes mellitus (DM) is considered to be a risk factor in carcinogenesis and progression, although the biological mechanisms are not well understood. Here we demonstrate that platelet-endothelial cell adhesion molecule 1 (PECAM-1) internalization drives β-catenin-mediated endot...

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Principais autores:	Qing Wu, Xingxing Du, Jianing Cheng, Xiuying Qi, Huan Liu, Xiaohong Lv, Xieyang Gong, Changxin Shao, Muhong Wang, Luxiao Yue, Xin Yang, Shiyu Li, Yafang Zhang, Xuemei Li, Huike Yang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-08-01
Series:	Cell Communication and Signaling
Assuntos:	Colon cancer Diabetes mellitus EndMT PECAM-1 β-catenin
Acceso en liña:	https://doi.org/10.1186/s12964-023-01193-2
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