One-Pot Phosphonylation of Heteroaromatic Lithium Reagents: The Scope and Limitations of Its Use for the Synthesis of Heteroaromatic Phosphonates

A one-pot lithiation–phosphonylation procedure was elaborated as a method to prepare heteroaromatic phosphonic acids. It relied on the direct lithiation of heteroaromatics followed by phosphonylation with diethyl chlorophosphite and then oxidation with hydrogen peroxide. This protocol provided the d...

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Autores principales:	Ewa Chmielewska, Natalia Miodowska, Błażej Dziuk, Mateusz Psurski, Paweł Kafarski
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-03-01
Colección:	Molecules
Materias:	aminophosphonates heteroaromatic lithiation phosphonylation phosphonic acids organophosphorus chemistry
Acceso en línea:	https://www.mdpi.com/1420-3049/28/7/3135
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