Immune checkpoint inhibitors in dMMR-MSI-H colorectal cancer: rationale, progress and prospects
Colorectal cancer (CRC) with a deficient mismatch repair and high microsatellite instability (dMMR–MSI-H) phenotype represents a biologically distinct subtype characterized by elevated tumor mutational burden and strong immunogenicity. These features contribute to their exceptional responsiveness to...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2026-07-01
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| Col·lecció: | Frontiers in Immunology |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fimmu.2026.1828717/full |
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