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Immunotherapy versus chemotherapy as adjuvant therapy for resected MSI-H/dMMR colorectal cancer: real-world evidence informing precision strategies

Background​​Immunotherapy has demonstrated unique advantages in MSI-H/dMMR colorectal cancer (CRC) for its later-line, first-line in metastatic status, and neoadjuvant therapy. However, evidence regarding its value in postoperative adjuvant therapy remains limited.Methods​​We retrospectively analyze...

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Uloženo v:
Hlavní autoři: Haifeng Sun, Pin Lyu, Shuaixi Yang, Fuqi Wang, Sifan Zhai, Mengfei Zhao, Weitang Yuan, Quanbo Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-10-01
Edice:Frontiers in Immunology
Témata:
colorectal cancer
microsatellite instability high
mismatch repair deficient
immunotherapy
adjuvant therapy
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1664684/full
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