Oxidative DNA Damage and Repair Dynamics in Multiple Sclerosis: Insights from Comet Assay Kinetics, Base Excision Repair Gene Expression, and Genotype Analysis

Multiple sclerosis (MS) is a neuroinflammatory disease where oxidative stress and DNA damage may influence disease progression. We investigated whether defects in base excision repair (BER) pathways contribute to MS by combining functional DNA repair assays, gene expression profiling, and genotype a...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Beata Filipek, Anna Macieja, Aleksandra Binda, Rafal Szelenberger, Leslaw Gorniak, Elzbieta Miller, Mariola Swiderek-Matysiak, Mariusz Stasiolek, Ireneusz Majsterek, Tomasz Poplawski
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2025-05-01
Rangatū:	Biomolecules
Ngā marau:	multiple sclerosis DNA repair oxidative stress comet assay base excision repair polymorphisms
Urunga tuihono:	https://www.mdpi.com/2218-273X/15/6/756
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!