Oxidative DNA Damage and Repair Dynamics in Multiple Sclerosis: Insights from Comet Assay Kinetics, Base Excision Repair Gene Expression, and Genotype Analysis

Multiple sclerosis (MS) is a neuroinflammatory disease where oxidative stress and DNA damage may influence disease progression. We investigated whether defects in base excision repair (BER) pathways contribute to MS by combining functional DNA repair assays, gene expression profiling, and genotype a...

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Autors principals:	Beata Filipek, Anna Macieja, Aleksandra Binda, Rafal Szelenberger, Leslaw Gorniak, Elzbieta Miller, Mariola Swiderek-Matysiak, Mariusz Stasiolek, Ireneusz Majsterek, Tomasz Poplawski
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-05-01
Col·lecció:	Biomolecules
Matèries:	multiple sclerosis DNA repair oxidative stress comet assay base excision repair polymorphisms
Accés en línia:	https://www.mdpi.com/2218-273X/15/6/756
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