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Considerations for the Use of the DNA Damage Marker γ‐H2AX in Disease Modeling, Detection, Diagnosis, and Prognosis

ABSTRACT Background DNA double‐strand breaks are known to be the most lethal kind of DNA damage as they cause genomic instability. Visualization and quantification of these breaks are possible via staining of the phosphorylated histone H2A variant H2AX at serine 139 with the anti‐phospho‐histone H2A...

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Autores principales: Holly Hosking, Wayne Pederick, Paul Neilsen, Andrew Fenning
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2024-09-01
Colección:Aging and Cancer
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Acceso en línea:https://doi.org/10.1002/aac2.12074
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