Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells

Abstract Background Acute myeloid leukemia (AML) is an aggressive malignancy only cured by intensive therapy. However, many elderly and unfit patients cannot receive such treatment due to an unacceptable risk of treatment-related morbidity and mortality. Disease-stabilizing therapy is then the only...

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Detalhes bibliográficos

Principais autores:	Håkon Reikvam, Randi Hovland, Rakel Brendsdal Forthun, Sigrid Erdal, Bjørn Tore Gjertsen, Hanne Fredly, Øystein Bruserud
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-09-01
coleção:	BMC Cancer
Assuntos:	Acute myeloid leukemia All-trans retinoic acid Valproic acid Gene expression profiling
Acesso em linha:	http://link.springer.com/article/10.1186/s12885-017-3620-y
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