Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells

Abstract Background Acute myeloid leukemia (AML) is an aggressive malignancy only cured by intensive therapy. However, many elderly and unfit patients cannot receive such treatment due to an unacceptable risk of treatment-related morbidity and mortality. Disease-stabilizing therapy is then the only...

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Egile Nagusiak:	Håkon Reikvam, Randi Hovland, Rakel Brendsdal Forthun, Sigrid Erdal, Bjørn Tore Gjertsen, Hanne Fredly, Øystein Bruserud
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2017-09-01
Saila:	BMC Cancer
Gaiak:	Acute myeloid leukemia All-trans retinoic acid Valproic acid Gene expression profiling
Sarrera elektronikoa:	http://link.springer.com/article/10.1186/s12885-017-3620-y
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