Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells

Abstract Background Acute myeloid leukemia (AML) is an aggressive malignancy only cured by intensive therapy. However, many elderly and unfit patients cannot receive such treatment due to an unacceptable risk of treatment-related morbidity and mortality. Disease-stabilizing therapy is then the only...

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Autori principali:	Håkon Reikvam, Randi Hovland, Rakel Brendsdal Forthun, Sigrid Erdal, Bjørn Tore Gjertsen, Hanne Fredly, Øystein Bruserud
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-09-01
Serie:	BMC Cancer
Soggetti:	Acute myeloid leukemia All-trans retinoic acid Valproic acid Gene expression profiling
Accesso online:	http://link.springer.com/article/10.1186/s12885-017-3620-y
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