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Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

Colorectal cancer (CRC) is one of the most common cancer worldwide. Chronic inflammation contributes to CRC development and progression. Emodin, is a natural anthraquinone derivative with anti-oxidant, anti-inflammatory, and anti-tumor activities. We used the AOM/DSS model of colitis-associated inte...

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Autori principali: Yunsha Zhang, Weiling Pu, Mélanie Bousquenaud, Sarah Cattin, Jelena Zaric, Li-kang Sun, Curzio Rüegg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-01-01
Serie:Frontiers in Oncology
Soggetti:
emodin
colorectal cancer
Chinese medicine
tumor microenvironment
inflammation
T lymphocytes
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2020.564674/full
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