Induction of colorectal carcinogenesis in the C57BL/6J and A/J mouse strains with a reduced DSS dose in the AOM/DSS model

Abstract Background Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide and thus mouse models of CRC are of significant value to study the pathogenesis. The Azoxymethane/Dextran sulfate sodium (AOM/DSS) model is a widely used, robust initiation-promotion model for chemi...

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Hlavní autoři:	Henriette Arnesen, Mette Helen Bjørge Müller, Mona Aleksandersen, Gunn Charlotte Østby, Harald Carlsen, Jan Erik Paulsen, Preben Boysen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-07-01
Edice:	Laboratory Animal Research
Témata:	AOM/DSS Colorectal cancer Mouse models Disease models Azoxymethane Dextran sulfate sodium
On-line přístup:	https://doi.org/10.1186/s42826-021-00096-y
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