A New Fungal Triterpene from the Fungus <i>Aspergillus flavus</i> Stimulates Glucose Uptake without Fat Accumulation

Through activity-guided fractionation, a new triterpene (asperflagin, <b>1</b>) was isolated as a PPAR-γ agonist from the jellyfish-derived fungus <i>Aspergillus flavus</i>. Asperflagin displayed selective and moderate transactivation effects on PPAR-γ in Ac2F rat liver cells. Based on further biolo...

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Bibliografische Detailangaben

Hauptverfasser:	Dan-dan Li, Ying Wang, Eun La Kim, Jongki Hong, Jee H. Jung
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-03-01
Schriftenreihe:	Marine Drugs
Schlagworte:	PPAR triterpenoid glucose uptake adipogenesis antidiabetic asperflagin
Online-Zugang:	https://www.mdpi.com/1660-3397/20/3/203
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