Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Summary: Waning immunity and emerging variants necessitate continued vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Improvements in vaccine safety, tolerability, and ease of manufacturing would benefit these efforts. Here, we develop a potent and easily manufacture...

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Detalhes bibliográficos

Principais autores:	Thayne H. Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L. Kwan, Nichole D. Salinas, Michael R. Holbrook, Lynn E. Lambert, Niraj H. Tolia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-03-01
coleção:	Cell Reports
Assuntos:	CP: Immunology CP: Microbiology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124723002772
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