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A combined designed CSP and Pfs48/45 infection and transmission blocking vaccine for malaria

Abstract The multiple stages of the malaria parasite life cycle hampers vaccine development. Combining a pre-erythrocytic antigen with a transmission-blocking antigen would target two independent stages of the life cycle for disease control, resulting in a multistage vaccine that can prevent infecti...

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Hlavní autoři: Richi Gupta, Thayne H. Dickey, Nichole D. Salinas, Palak N. Patel, Rui Ma, Dashuang Shi, Myesha Singleton, Tarik Ouahes, Thao P. Pham, Kazutoyo Miura, Carole A. Long, Lynn E. Lambert, Niraj H. Tolia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-09-01
Edice:npj Vaccines
On-line přístup:https://doi.org/10.1038/s41541-025-01262-2
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