Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Abstract Apical membrane antigen 1 (AMA1) is a key malaria vaccine candidate and target of neutralizing antibodies. AMA1 binds to a loop in rhoptry neck protein 2 (RON2L) to form the moving junction during parasite invasion of host cells, and this complex is conserved among apicomplexan parasites. A...

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Bibliografiske detaljer

Principais autores:	Palak N. Patel, Thayne H. Dickey, Ababacar Diouf, Nichole D. Salinas, Holly McAleese, Tarik Ouahes, Carole A. Long, Kazutoyo Miura, Lynn E. Lambert, Niraj H. Tolia
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-09-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-023-40878-7
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