Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens

Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been found to increase susceptibility to bacterial superinfections leading to increased morbidity and mortality. The molecular mechanisms underlying HMPV-mediated increase in bacteri...

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Bibliografski detalji

Glavni autori:	Simon Loevenich, Nicola P. Montaldo, Arthur Wickenhagen, Tatyana Sherstova, Barbara van Loon, Victor Boyartchuk, Marit W. Anthonsen
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2023-06-01
Serija:	Frontiers in Immunology
Teme:	human metapneumovirus co-infection airway bacteria proinflammatory cytokines inflammasome IFN-β
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1173605/full
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