Trans-cyclooctene—a Swiss army knife for bioorthogonal chemistry: exploring the synthesis, reactivity, and applications in biomedical breakthroughs
Abstract Background Trans-cyclooctenes (TCOs) are highly strained alkenes with remarkable reactivity towards tetrazines (Tzs) in inverse electron-demand Diels–Alder reactions. Since their discovery as bioorthogonal reaction partners, novel TCO derivatives have been developed to improve their reactiv...
Zapisane w:
| Główni autorzy: | , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
SpringerOpen
2024-06-01
|
| Seria: | EJNMMI Radiopharmacy and Chemistry |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s41181-024-00275-x |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|