The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

Alzheimer's disease (AD) is the most common neurodegenerative disease, with an increasing prevalence. Currently, there is no ideal diagnostic molecular imaging agent for diagnosing AD. Antibodies (Abs) have been proposed to close this gap as they can bind selectively and with high affinity to amyloi...

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Bibliografski detalji

Glavni autori:	Sara Lopes van den Broek, Dag Sehlin, Jens V. Andersen, Blanca I. Aldana, Natalie Beschörner, Maiken Nedergaard, Gitte M. Knudsen, Stina Syvänen, Matthias M. Herth
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-09-01
Serija:	Frontiers in Nuclear Medicine
Teme:	Alzheimer’s disease amyloid beta tetrazine ligation pretargeted autoradiography tetrazine trans-cyclooctene
Online pristup:	https://www.frontiersin.org/articles/10.3389/fnume.2022.1001722/full
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