Memory B-cell derived donor-specific antibodies do not predict outcome in sensitized kidney transplant recipients: a retrospective single-center study

BackgroundRepeated exposure to sensitizing events can activate HLA-specific memory B cells, leading to the production of donor-specific memory B cell antibodies (DSAm) that pose a risk for antibody-mediated rejection (ABMR) in kidney transplant recipients (KTRs). This single-center retrospective stu...

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Principais autores:	Dania Altulea, Joost C. van den Born, Arjan Diepstra, Laura Bungener, Dagmar Terpstra, Bouke G. Hepkema, Rosa Lammerts, Peter Heeringa, Sebastiaan Heidt, Henny Otten, Leon Reteig, Gonca E. Karahan, Stefan P. Berger, Jan-Stephan Sanders
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-04-01
Colecção:	Frontiers in Immunology
Assuntos:	memory B cells DSA polyclonal activation IgG production ABMR
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1360627/full
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