Memory B-cell derived donor-specific antibodies do not predict outcome in sensitized kidney transplant recipients: a retrospective single-center study

BackgroundRepeated exposure to sensitizing events can activate HLA-specific memory B cells, leading to the production of donor-specific memory B cell antibodies (DSAm) that pose a risk for antibody-mediated rejection (ABMR) in kidney transplant recipients (KTRs). This single-center retrospective stu...

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Autori principali:	Dania Altulea, Joost C. van den Born, Arjan Diepstra, Laura Bungener, Dagmar Terpstra, Bouke G. Hepkema, Rosa Lammerts, Peter Heeringa, Sebastiaan Heidt, Henny Otten, Leon Reteig, Gonca E. Karahan, Stefan P. Berger, Jan-Stephan Sanders
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-04-01
Serie:	Frontiers in Immunology
Soggetti:	memory B cells DSA polyclonal activation IgG production ABMR
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1360627/full
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