IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis

Abstract Background Interleukin-6 (IL-6) plays a central role in sepsis-induced cytokine storm involving immune hyperactivation and early neutrophil activation. Programmed death protein-1 (PD-1) is associated with sepsis-induced immunosuppression and lymphocyte apoptosis. However, the effects of sim...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Song I Lee, Na Young Kim, Chaeuk Chung, Dongil Park, Da Hyun Kang, Duk Ki Kim, Min-Kyung Yeo, Pureum Sun, Jeong Eun Lee
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2025-01-01
Sarja:	BMC Immunology
Aiheet:	Activation, Lymphocyte Activation, Neutrophil Interleukin 6 Sepsis
Linkit:	https://doi.org/10.1186/s12865-024-00679-z
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!