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Epigenetic agents, zebularine and valproic acid, inhibit the growth of the oral squamous cell carcinoma cell line HSC4 in vitro and in vivo
Abstract Objectives This study explored the potential of Zebularine (Zeb), a DNA methyltransferase inhibitor (DNMTi), and Valproic acid (Vpa), a histone deacetylase inhibitor (HDACi), as a combined treatment strategy for OSCC. Materials and methods OSCC cell lines, HSC4 (well-differentiated type) an...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer
2025-07-01
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| Seri Bilgileri: | Discover Oncology |
| Konular: | |
| Online Erişim: | https://doi.org/10.1007/s12672-025-02928-y |
| Etiketler: |
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