Direct reprogramming of epithelial cell rests of malassez into mesenchymal-like cells by epigenetic agents

The DNA demethylating agent, 5-Azacytidine (5Aza), and histone deacetylase inhibitor, valproic acid (Vpa), can improve the reprogramming efficiencies of pluripotent cells. This study aimed to examine the roles of 5Aza and Vpa in the dedifferentiation of epithelial cell rests of Malassez (ERM) into s...

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Published in:Sci Rep
Main Authors: Yoshida, Koki, Uehara, Osamu, Kurashige, Yoshihito, Paudel, Durga, Onishi, Aya, Neopane, Puja, Hiraki, Daichi, Morikawa, Tetsuro, Harada, Fumiya, Takai, Rie, Sato, Jun, Saitoh, Masato, Abiko, Yoshihiro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817677/
https://ncbi.nlm.nih.gov/pubmed/33473142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79426-4
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