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IL-38 Alleviates Inflammation in Sepsis in Mice by Inhibiting Macrophage Apoptosis and Activation of the NLRP3 Inflammasome

Interleukin- (IL-) 38 is an emerging cytokine with multiple functions involved in infection and immunity. However, the potential role of IL-38 in the host immune response during sepsis remains elusive. Herein, we investigated if macrophages in septic mice express IL-38, the molecular mechanisms behi...

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Autores principales: Yun Ge, Juan Chen, Yanting Hu, Xinyi Chen, Man Huang
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2021-01-01
Colección:Mediators of Inflammation
Acceso en línea:http://dx.doi.org/10.1155/2021/6370911
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