Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling

Inflammatory caspase-11 senses and is activated by intracellular lipopolysaccharide (LPS) leading to pyroptosis that has critical role in defensing against bacterial infection, whereas its excess activation under pathogenic circumstances may cause various inflammatory diseases. However, there are fe...

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主要な著者:	Jiezhou Ye, Bo Zeng, Meiyan Zhong, Hongchun Li, Lihui Xu, Junxiang Shu, Yaofeng Wang, Fan Yang, Chunsu Zhong, Xunjia Ye, Xianhui He, Dongyun Ouyang
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2021-01-01
シリーズ:	Acta Pharmaceutica Sinica B
主題:	Caspase-11 Macrophages Gasdermin D Pyroptosis Scutellarin PKA signaling
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211383520306560
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