Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation

Evodiamine is a major ingredient of the plant Evodia rutaecarpa, which has long been used for treating infection-related diseases including diarrhea, beriberi and oral ulcer, but the underlying mechanism is unclear. Here we aimed to explore whether evodiamine influenced NLRP3 (NLR family, pyrin cont...

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Detalhes bibliográficos

Principais autores:	Chen-Guang Li, Qiong-Zhen Zeng, Ming-Ye Chen, Li-Hui Xu, Cheng-Cheng Zhang, Feng-Yi Mai, Chen-Ying Zeng, Xian-Hui He, Dong-Yun Ouyang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-03-01
coleção:	Frontiers in Pharmacology
Assuntos:	evodiamine acetylation NLRP3 inflammasome α-tubulin pyroptosis
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.00290/full
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