Hippocampal Adult Neurogenesis Is Maintained by Neil3-Dependent Repair of Oxidative DNA Lesions in Neural Progenitor Cells

Accumulation of oxidative DNA damage has been proposed as a potential cause of age-related cognitive decline. The major pathway for removal of oxidative DNA base lesions is base excision repair, which is initiated by DNA glycosylases. In mice, Neil3 is the main DNA glycosylase for repair of hydantoi...

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Detalhes bibliográficos

Principais autores:	Christine Elisabeth Regnell, Gunn Annette Hildrestrand, Yngve Sejersted, Tirill Medin, Olve Moldestad, Veslemøy Rolseth, Silje Zandstra Krokeide, Rajikala Suganthan, Luisa Luna, Magnar Bjørås, Linda H. Bergersen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2012-09-01
coleção:	Cell Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124712002331
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