Berberine ameliorates septic cardiomyopathy through protecting mitochondria and upregulating Notch1 signaling in cardiomyocytes

IntroductionSeptic cardiomyopathy (SCM) arises as a consequence of sepsis-associated cardiovascular dysfunction, for which there is currently no specific targeted therapy available. Previous studies have demonstrated the beneficial therapeutic effect of berberine (BBR) on SCM; however, the underlyin...

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Detalhes bibliográficos

Principais autores:	Qi Shen, Yufan Yuan, Zelin Li, Ying Ling, Jian Wang, Mingjing Gao, Peng Wang, Mengli Li, Lizhong Lai, Jinlan Jin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-11-01
coleção:	Frontiers in Pharmacology
Assuntos:	septic cardiomyopathy mitochondria Notch1 signaling pathway berberine cardiomyocytes
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1502354/full
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