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Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells.

The Suppressors of Cytokine Signalling (SOCS) proteins are negative regulators of cytokine signalling required to prevent excess cellular responses. SOCS1 and SOCS3 are essential to prevent inflammatory disease, SOCS1 by attenuating responses to IFNγ and gamma-common (γc) cytokines, and SOCS3 via re...

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Detalhes bibliográficos
Principais autores: Takashi Ushiki, Nicholas D Huntington, Stefan P Glaser, Hiu Kiu, Angela Georgiou, Jian-Guo Zhang, Donald Metcalf, Nicos A Nicola, Andrew W Roberts, Warren S Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC5008821?pdf=render
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