Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation

Abstract Background DNA methylation (DNAm) is a critical regulator of both development and cellular identity and shows unique patterns in neurons. To better characterize maturational changes in DNAm patterns in these cells, we profile the DNAm landscape at single-base resolution across the first two...

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Bibliografische gegevens

Hoofdauteurs:	Amanda J. Price, Leonardo Collado-Torres, Nikolay A. Ivanov, Wei Xia, Emily E. Burke, Joo Heon Shin, Ran Tao, Liang Ma, Yankai Jia, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, Andrew E. Jaffe
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2019-09-01
Reeks:	Genome Biology
Onderwerpen:	DNA methylation Neurodevelopment Gene expression Non-CpG methylation
Online toegang:	http://link.springer.com/article/10.1186/s13059-019-1805-1
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