The GPR17 agonist galinex restores oligodendrocyte maturation under inflammatory conditions

IntroductionChronic neuroinflammation disrupts oligodendrocyte differentiation and limits effective remyelination across multiple neurological disorders. Among the molecular regulators integrating inflammatory cues with oligodendrocyte maturation, G protein-coupled receptor 17 (GPR17) has emerged as...

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Bibliografske podrobnosti

Principais autores:	Juliana Helena Castro e Silva, Davide Marangon, Marta Boccazzi, Stefano Raffaele, Nicolò Cignitti, Martina Bavetta, Ivan Arisi, Marta Fumagalli, Maria P. Abbracchio, Davide Lecca
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-06-01
Serija:	Frontiers in Pharmacology
Teme:	GPR17 neuroinflammation oligodendrocyte oligodendrocyte precursor cell (OPC) pro-inflammatory cytokines
Online dostop:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1838997/full
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