Microglial HDAC3 inhibits the migration of CD8-positive T cell in the development of EAE by restraining the expression of CCL5
Abstract Background Multiple sclerosis (MS) is a central nervous system disease caused by auto-immune reaction induced demyelination, however, the molecular mechanism of MS remains unclear. Previous study revealed that histone deacetylase 3 (HDAC3) is upregulated in the spinal cord of MS patient. He...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2026-03-01
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| Серии: | Cell & Bioscience |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1186/s13578-026-01564-5 |
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