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Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.

A critical step in X-chromosome inactivation (XCI), which results in the dosage compensation of X-linked gene expression in mammals, is the coating of the presumptive inactive X chromosome by the large noncoding Xist RNA, which then leads to the recruitment of other factors essential for the heteroc...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Constance Ciaudo, Agnès Bourdet, Michel Cohen-Tannoudji, Harry C Dietz, Claire Rougeulle, Philip Avner
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2006-06-01
Цуврал:PLoS Genetics
Онлайн хандалт:http://europepmc.org/articles/PMC1479048?pdf=render
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