Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.
A critical step in X-chromosome inactivation (XCI), which results in the dosage compensation of X-linked gene expression in mammals, is the coating of the presumptive inactive X chromosome by the large noncoding Xist RNA, which then leads to the recruitment of other factors essential for the heteroc...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2006-06-01
|
| Seri Bilgileri: | PLoS Genetics |
| Online Erişim: | http://europepmc.org/articles/PMC1479048?pdf=render |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|