HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells
<p>Abstract</p> <p>Background</p> <p>Lens epithelium–derived growth factor (LEDGF/p75) is a cellular co-factor of HIV-1 integrase (IN) that tethers the viral pre-integration complex to the host cell chromatin and determines the genome wide integration site distribution pattern of HIV-1. Recently, we...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2012-10-01
|
| Serie: | Retrovirology |
| Soggetti: | |
| Accesso online: | http://www.retrovirology.com/content/9/1/84 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|