Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium

Abstract Background Loss of CFTR-dependent anion and fluid secretion in the ducts of the exocrine pancreas is thought to contribute to the development of pancreatitis, but little is known about the impact of inflammation on ductal CFTR function. Here we used adult stem cell-derived cell cultures (or...

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Principais autores:	Dora Angyal, Tessa A. Groeneweg, Anny Leung, Max Desain, Kalyan Dulla, Hugo R. de Jonge, Marcel J. C. Bijvelds
格式:	Artigo
語言:	Inglês
出版:	BMC 2024-01-01
叢編:	Cellular & Molecular Biology Letters
主題:	CFTR Cystic fibrosis Cytokines Epithelial ion transport Organoid Pancreatitis
在線閱讀:	https://doi.org/10.1186/s11658-024-00537-1
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