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Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium

Abstract Background Loss of CFTR-dependent anion and fluid secretion in the ducts of the exocrine pancreas is thought to contribute to the development of pancreatitis, but little is known about the impact of inflammation on ductal CFTR function. Here we used adult stem cell-derived cell cultures (or...

Deskribapen osoa

Gorde:
Egile Nagusiak: Dora Angyal, Tessa A. Groeneweg, Anny Leung, Max Desain, Kalyan Dulla, Hugo R. de Jonge, Marcel J. C. Bijvelds
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2024-01-01
Saila:Cellular & Molecular Biology Letters
Gaiak:
CFTR
Cystic fibrosis
Cytokines
Epithelial ion transport
Organoid
Pancreatitis
Sarrera elektronikoa:https://doi.org/10.1186/s11658-024-00537-1
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