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Protein embeddings predict binding residues in disordered regions

Abstract The identification of protein binding residues helps to understand their biological processes as protein function is often defined through ligand binding, such as to other proteins, small molecules, ions, or nucleotides. Methods predicting binding residues often err for intrinsically disord...

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Auteurs principaux: Laura R. Jahn, Céline Marquet, Michael Heinzinger, Burkhard Rost
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2024-06-01
Collection:Scientific Reports
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Accès en ligne:https://doi.org/10.1038/s41598-024-64211-4
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