An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities

Abstract Background Tumor-targeting IgE antibodies have elicited potent tumor-restricting effects by recruiting immune effector mechanisms. However, a dedicated platform for the generation, selection and evaluation of novel IgEs based on target antigen recognition and functional profiles has not bee...

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Principais autores:	Lais C. G. F. Palhares, Melanie Grandits, Katie Stoker, Jitesh Chauhan, Heng Sheng Sow, Gilbert O. Fruhwirth, Sophia Tsoka, James Birtley, Leanne Partington, Tim Wilson, Elizabeth Hardaker, Sophia N. Karagiannis, Heather J. Bax, Kevin FitzGerald
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2025-02-01
סדרה:	Journal of Experimental & Clinical Cancer Research
נושאים:	Breast Cancer HER2 IgE Immunotherapy
גישה מקוונת:	https://doi.org/10.1186/s13046-025-03319-5
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!