An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities
Abstract Background Tumor-targeting IgE antibodies have elicited potent tumor-restricting effects by recruiting immune effector mechanisms. However, a dedicated platform for the generation, selection and evaluation of novel IgEs based on target antigen recognition and functional profiles has not bee...
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| Principais autores: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2025-02-01
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| Serier: | Journal of Experimental & Clinical Cancer Research |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s13046-025-03319-5 |
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