Analysis of follow-up data in large biobank cohorts: a review of methodology
This study focuses on key methodological challenges in genome-wide association studies (GWAS) of biobank data with time-to-event outcomes, analyzed using the Cox proportional hazards (CPH) model. We address four primary issues: left-truncation of the data, computational inefficiency of standard mode...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2025-06-01
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| Серія: | Frontiers in Genetics |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1534726/full |
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