Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

Abstract Background Neuroinflammation plays a critical role in the onset and development of neurodegeneration disorders such as Parkinson’s disease. The immune activities of the central nervous system are profoundly affected by peripheral immune activities. Immune tolerance refers to the unresponsiv...

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Detalhes bibliográficos

Principais autores:	Yang Liu, Xin Xie, Li-Ping Xia, Hong Lv, Fan Lou, Yan Ren, Zhi-Yi He, Xiao-Guang Luo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-11-01
coleção:	Journal of Neuroinflammation
Assuntos:	Microglia Peripheral blood monocytes Neuroinflammation Neuroprotection Neurodegeneration disease
Acesso em linha:	http://link.springer.com/article/10.1186/s12974-017-0994-3
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