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Computational Recognition and Clinical Verification of TGF-β-Derived miRNA Signature With Potential Implications in Prognosis and Immunotherapy of Intrahepatic Cholangiocarcinoma

MicroRNAs (miRNAs) were recently implicated in modifying the transforming growth factor β (TGF-β) signaling in multiple cancers. However, TGF-β-derived miRNAs and their potential clinical significance remain largely unexplored in intrahepatic cholangiocarcinoma (ICC). In this study, we proposed an i...

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Principais autores: Zaoqu Liu, Siyuan Weng, Hui Xu, Libo Wang, Long Liu, Yuyuan Zhang, ChunGuang Guo, Qin Dang, Zhe Xing, Taoyuan Lu, Xinwei Han
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-10-01
coleção:Frontiers in Oncology
Assuntos:
intrahepatic cholangiocarcinoma
microRNAs
TGF-β
prognosis
recurrence
immunotherapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.757919/full
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