Genetic alterations of KRAS and TP53 in intrahepatic cholangiocarcinoma associated with poor prognosis

The aim of this study is to investigate certain genetic features of intrahepatic cholangiocarcinoma (ICCA). A total of 12 eligible ICCA patients were enrolled, and tumor tissues from the patients were subjected to next-generation sequencing of a multi-genes panel. Tumor mutation burden (TMB), mutate...

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Detalhes bibliográficos

Principais autores:	Peng Jianbo, Fang Shuo, Li Meisheng, Liu Yuxin, Liang Xiaolu, Li Zuobiao, Chen Gaohui, Peng Lijiao, Chen Nianping, Liu Lei, Xu Xiaohong, Dai Wei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	De Gruyter 2023-07-01
coleção:	Open Life Sciences
Assuntos:	intrahepatic cholangiocarcinoma next-generation sequencing genetic profile tumor mutation burden prognosis analysis
Acesso em linha:	https://doi.org/10.1515/biol-2022-0652
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